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Bumex or Lasix: what is best for me? Such loop diuretics as furosemide and bumetanide are characterized by a rapid but short-lived diuretic effect, which increases with increasing doses. After oral administration, the diuretic effect occurs within 30-60 minutes and lasts 4-9 hours; after intravenous administration, the effect develops within 5-15 minutes and lasts 2-3 hours.

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Loop diuretic conversion - Equivalent Doses Furosemide (Lasix) 40 mg PO = Furosemide 20 mg IV = Torsemide 20 mg PO/IV = Bumetanide (Bumex) 1 mg PO/IV #Pharmacology

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Renal impairment may reduce clearance and warrant the use of higher doses with extended dosing intervals. Torsemide may be less effective in these patients and delayed excretion of the drug may increase the risk of toxicity. 2015-01-01 · Thus the relative potency of bumetanide especially and torsemide compared to furosemide is reduced in patients with impaired kidney function.

A sulfa moiety containing loop diuretics (  9 Jan 2020 Bumetanide and torsemide have oral bioavailability >80% (so IV to PO Furosemide will typically cause diuresis for <6 hours (“LASIX” was so  10 Apr 2015 Torsemide – what dose?? Current furosemide dose 18.75 mg PO BID with 12.5 mg midday (CHF controlled). = 50 mg/day furosemide ÷  2019. máj. 31.